08:30 – 09:00 Opening ceremony and welcome addresses Emiliana Konova, Elissaveta Naumova, Dobroslav Kyurkchiev
Session 1: “The current knowledge of successes and failures in reproduction” Chairpersons: Gavin Sacks and Emiliana Konova
Plenary lectures
09:00 – 09:20 Is reproductive failure an autoimmune disease? Gavin Sacks
09:20 – 09:40 KIR and HLA - Basic concepts and role in pregnancy outcome Elissaveta Naumova
09:40 – 10:00 Silenced Tregs in pregnancy failure Velislava Terzieva
10:00 – 10:20 Human umbilical cord mesenchymal stem cells secrete immunosuppressive cytokines and express PD-1L. Dobroslav Kyurkchiev
10:20 – 11:00 Discussion and coffee break
11:00 – 11:20 Thrombophilic gene mutations and what should we do to control the problem in reproductive failures Roumen Roussev
11:20 – 11:40 Uterine microbiota and pregnancy loss: the role of the immune response Emiliana Konova
11:40 – 12:00 Immune therapies for reproductive failure Gavin Sacks
12:00 – 12:30 Discussion
12:30 – 13:30 Lunch
Session 2-1: “New Horizons: Presentation of Projects”
Chairpersons: Elissaveta Naumova and Dobroslav Kyurkchiev
13:30 – 13:40 KIR and HLA genotyping in evaluation of reproductive failures - current status and future directions Anastasiya Mihaylova
13:40 – 13:50 The role of KIR and KIR-HLA interactions in reproduction Gabriel Elmadjian
13:50 – 14:00 Human umbilical cord mesenchymal stem cells exhibit different behaviour when primed with Interferon-γ. Kalina Belemesova
14:00 – 14:10 Cryopreservation of human endometrial stromal cells negatively affects their in vitro decidualization potential and cytokine production I. Bochev, K. Belemezova, S. Kyurkchiev
14:10 – 14:20 Practical medical application of stem cell therapy for endometrium regeneration and ovarian rejuvenation. Popov Cv., Popova A., Gincheva D., Ivanov P., Bodurska T., Konova E.
14.20 – 14.30 Study of endometrial immune profile in patients with impaired endometrial microbiome Blazheva S., Pachkova S., Gincheva D., Ivanov P., Bodurska T., Konova E.
14.30 – 15.00 Discussion
15:00 – 15:30 Coffee break
Session 2-2: “New Horizons: Presentation of Projects” Chairpersons: Velislava Terzieva and Roumen Roussev
15:30 – 15:40 Predictive value of DR+Tregs in women with recurrent pregnancy loss Velislava Terzieva
15.40 – 15.50 Some key molecular factors in early pregnancy Kameliya Vinketova, Iliya Karagyozov, Ivan Bochev, Shina Pashova, George Boyadzhiev, Yoana Dimitrova, Emilia Alova, Vesselina Koleva, Milena Mourdjeva, Tsvetelina Oreshkova
15:50 – 16:00 Reproductive carrier screening for genetic conditions in Bulgaria Katia Kovacheva
16:00 – 16:10 Food intolerance as part of post pregnancy "overlap syndrome"? - Case based review Ekaterina Ivanova-Todorova
16:10 – 16:20 NatАspin H Violeta Stratieva
16:20 – 16:30 Autoimmune disease associated alterations in the reproductive system in a mouse model of Systemic lupus erythematosus Gabriela Boneva, Nikolina Mihaylova, József Prechl, Stefka Delimitreva, Andrey Tchorbanov
